Duke Nukem 3D requires data files from the original copy of the game.
Create a directory named share to your memory card, go to that directory 
and create another directory named duke3d. Then go that directory and copy
the file DUKE3D.GRP from your computer there and start the game.

Controls are modified for tablets that don't have a keyboard
but you can of course change them in game. Controls are:

Stylus: Look around
Direction pad: Move
Direction pad select: Fire
Zoom out: Previous Weapon
Zoom in: Next Weapon
Fullscreen: Jump

Menu key works as a modifier key:

Menu + Direction pad select: Use Inventory Item
Menu + Zoom out: Previous Item
Menu + Zoom in: Next item
Menu + Fullscreen: Crouch
Menu + Esc: Open
